Central serous chorioretinopathy treatment with a systemic PDE5 and PDE6 inhibitor (sildenafil)
Purpose: Examine the use of systemic phosphodiesterase inhibition (sildenafil) to clear central serous chorioretinopathy (CSCR).Observations: In Container Lid Cover a long-standing CSCR patient, sildenafil produced a rapid resolution.When discontinued (dechallenge) the CSCR returned.When rechallenged, the CSCR again rapidly disappeared and did not